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. 1994 Jan 15;343(8890):146-7.
doi: 10.1016/s0140-6736(94)90935-0.

Single-breath nitric oxide measurements in asthmatic patients and smokers

M G Persson  1 , O Zetterström, V Agrenius, E Ihre, L E Gustafsson
Affiliations

Single-breath nitric oxide measurements in asthmatic patients and smokers

M G Persson et al. Lancet. .

Abstract

Exhaled nitric oxide (NO) concentrations were measured in asthmatic outpatients and in non-smoking and smoking healthy controls. In single exhalations, NO showed a peak suggestive of airway origin in both controls and asthmatic patients. The peak NO concentration was higher in asthmatic patients and lower in smokers than in non-smoking controls (p < 0.05). The findings support a role for NO in the host defence response in asthma and suggest that NO measurements can discriminate between different types of lung disorders.

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