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Clinical Trial
. 1976 Aug 25;168(2):81-7.
doi: 10.1007/BF01851897.

Effects of L-thyroxine in acute renal failure

E Straub
Clinical Trial

Effects of L-thyroxine in acute renal failure

E Straub. Res Exp Med (Berl). .

Abstract

Eight pediatric patients presenting with acute renal failure (shock kidney, anuria continuing for three to five days) were treated with L-thyroxine (p.o. 5-6 mug per kg per day). Dialysis was not used. Diuresis started within 34 to 46 hours. Serum levels of urea and creatinine normalized within a very short time. The results are discussed on the basis of a new hypothesis concerning the RPF- and GFR-raising action of thyroid hormone in the normal situation and in acute renal failure.

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