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Review
. 1994 May 14;343(8907):1199-206.
doi: 10.1016/s0140-6736(94)92405-8.

Nitric oxide: mediator, murderer, and medicine

E Anggård  1
Affiliations
Review

Nitric oxide: mediator, murderer, and medicine

E Anggård. Lancet. .

Abstract

In the past ten years several research fields have converged to show that the tiny molecule nitric oxide (NO), a reactive gas, functions both as a signalling molecule in endothelial and nerve cells and as a killer molecule by activated immune cells--and it can be used as a new medicine by inhalation. This article reviews the biology of this remarkable molecule and discusses the implications for clinical medicine.

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Comment in

  • Clinical relevance of nitric oxide in the gut.
    Boeckxstaens GE, Mebis J, Janssens J, Geboes K, De Man JG, Herman AG, Pelckmans PA. Boeckxstaens GE, et al. Lancet. 1994 Jul 9;344(8915):129. doi: 10.1016/s0140-6736(94)91315-3. Lancet. 1994. PMID: 7912364 No abstract available.

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