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. 1976 Oct;10(4):765-7.
doi: 10.1128/AAC.10.4.765.

Correlation of resistance to proflavine and penicillin in Escherichia coli

R C McKellar, C N McKenzie, K J Kushner

Correlation of resistance to proflavine and penicillin in Escherichia coli

R C McKellar et al. Antimicrob Agents Chemother. 1976 Oct.

Abstract

A number of proflavine (PF)-resistant mutants of Escherichia coli B were also resistant to penicillin and cephalothin. Mutants resistant to 1.0 mM PF were 10 times more penicillin resistant than were the PF-susceptible, wild-type cells. Single-step mutants selected for resistance to either PF or penicillin were also resistant to the other drug. None of the resistant mutants tested possessed beta-lactamase activity. These results suggest that resistance to PF and penicillin in E. coli B may be due to permeability changes in the cell envelope.

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References

    1. J Infect Dis. 1973 Sep;128(3):321-30 - PubMed
    1. Proc Natl Acad Sci U S A. 1965 Jan;53:24-30 - PubMed
    1. Adv Microb Physiol. 1973;9:31-88 - PubMed
    1. Antimicrob Agents Chemother. 1973 Sep;4(3):332-6 - PubMed
    1. J Mol Biol. 1974 Oct 15;89(1):17-32 - PubMed

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