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Review
. 1994 Jun;6(3):451-9.
doi: 10.1016/0955-0674(94)90039-6.

Cell cycle regulated transcription in yeast

C Koch  1 , K Nasmyth
Affiliations
Review

Cell cycle regulated transcription in yeast

C Koch et al. Curr Opin Cell Biol. 1994 Jun.

Abstract

At least four different classes of cell cycle regulated gene exist in yeast: G1 cyclins and DNA synthesis genes are expressed in late G1; histone genes in S phase; genes for transcription factors, cell cycle regulators and replication initiation proteins in G2; and genes needed for cell separation as cells enter G1. Early and late G1-specific transcription is mediated by the Swi5/Ace2 and Swi4/Swi6 classes of factor, respectively. Changes in cyclin/Cdc28 kinases may be involved in all classes of regulation. Transcriptional control of cyclin genes has an important role in regulating cell cycle progression.

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