Cyclophosphamide pretreatment and protection against malaria
- PMID: 791863
- PMCID: PMC415498
- DOI: 10.1128/iai.14.4.1103-1105.1976
Cyclophosphamide pretreatment and protection against malaria
Abstract
Mice pretreated with cyclophosphamide were able to overcome infection from a lethal malarial strain. The development of resistance was preceded by increased hypersensitivity to malarial antigens. Hypersensitivity was demonstrable by a delayed footpad swelling technique.
Similar articles
-
Delayed immune reactions in mice immunized with malarial antigen.Am J Trop Med Hyg. 1977 May;26(3):377-81. doi: 10.4269/ajtmh.1977.26.377. Am J Trop Med Hyg. 1977. PMID: 326066
-
Immune response studies in relation to protection induced by using MDP as an adjuvant in malaria.Immunol Invest. 1988 Mar;17(1):1-17. doi: 10.3109/08820138809055714. Immunol Invest. 1988. PMID: 3292412
-
Failure to protect Mus musculus against Plasmodium berghei with footpad injections of killed parasites incorporated in complete Freund's adjuvant.J Parasitol. 1975 Oct;61(5):937-40. J Parasitol. 1975. PMID: 1102649
-
Liver or blood-stage arrest during malaria sporozoite immunization: the later the better?Trends Parasitol. 2013 Jun;29(6):304-10. doi: 10.1016/j.pt.2013.03.008. Epub 2013 Apr 20. Trends Parasitol. 2013. PMID: 23608185 Review.
-
The role of intrahepatic lymphocytes in mediating protective immunity induced by attenuated Plasmodium berghei sporozoites.Immunol Rev. 2000 Apr;174:123-34. doi: 10.1034/j.1600-0528.2002.00013h.x. Immunol Rev. 2000. PMID: 10807512 Review.
Cited by
-
Cyclophosphamide effects on murine cryptococcosis.Infect Immun. 1978 Aug;21(2):674-7. doi: 10.1128/iai.21.2.674-677.1978. Infect Immun. 1978. PMID: 689741 Free PMC article.
-
Two distinct types of non-specific immunosuppression in murine malaria.Clin Exp Immunol. 1980 Dec;42(3):428-35. Clin Exp Immunol. 1980. PMID: 7011609 Free PMC article.
-
Host defence mechanisms, antibiotics and immunosuppressive agents--a complex relationship.Eur J Clin Microbiol. 1984 Aug;3(4):285-7. doi: 10.1007/BF01977474. Eur J Clin Microbiol. 1984. PMID: 6489320 No abstract available.
-
Prevention of recrudescent malaria in nude mice by thymic grafting or by treatment with hyperimmune serum.Infect Immun. 1977 Jun;16(3):821-6. doi: 10.1128/iai.16.3.821-826.1977. Infect Immun. 1977. PMID: 330396 Free PMC article.
-
Host defenses in murine malaria: evaluation of the mechanisms of immunity to Plasmodium yoelii infection.Infect Immun. 1979 Feb;23(2):384-91. doi: 10.1128/iai.23.2.384-391.1979. Infect Immun. 1979. PMID: 422246 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources