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. 1976 Nov 12;49(4):343-7.
doi: 10.1007/BF00496138.

Enterochromaffin cells as the endocrine source of gastrointestinal substance P

P Heitz, J M Polak, D M Timson, A G Pearse

Enterochromaffin cells as the endocrine source of gastrointestinal substance P

P Heitz et al. Histochemistry. .

Abstract

Immunoreactive Substance P is localized in the intramural neural plexuses of mammalian intestine, and in endocrine cells in the intestinal mucosa which have now been identified as enterochromaffin (EC). The presence of a neurotransmitter peptide in these cells favours the hypothesis of their neuroectodermal origin.

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