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. 1994 Sep 15;50(9):846-9.
doi: 10.1007/BF01956469.

Inhibition of the growth of cariogenic bacteria in vitro by plant flavanones

H Tsuchiya  1 , M Sato, M Iinuma, J Yokoyama, M Ohyama, T Tanaka, I Takase, I Namikawa
Affiliations

Inhibition of the growth of cariogenic bacteria in vitro by plant flavanones

H Tsuchiya et al. Experientia. .

Abstract

Phytoalexins, defensive compounds produced by plants against microbial infections, were purified from Sophora exigua (Leguminosae) and their growth inhibitory effects on oral cariogenic bacteria were determined in vitro. Among three isolated compounds, 5,7,2',4'-tetrahydroxy-8-lavandulylflavanone completely inhibited the growth of oral bacteria including primary cariogenic mutans streptococci, other oral streptococci, actinomycetes, and lactobacilli, at concentrations of 1.56 to 6.25 micrograms/ml.

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