Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Oct;94(4):437-40.
doi: 10.1007/BF00201608.

Refined localization of TSC1 by combined analysis of 9q34 and 16p13 data in 14 tuberous sclerosis families

B Janssen  1 , J Sampson, M van der Est, W Deelen, S Verhoef, I Daniels, A Hesseling, P Brook-Carter, M Nellist, D Lindhout, et al.
Affiliations

Refined localization of TSC1 by combined analysis of 9q34 and 16p13 data in 14 tuberous sclerosis families

B Janssen et al. Hum Genet. 1994 Oct.

Abstract

Tuberous sclerosis (TSC) is a heterogeneous trait. Since 1990, linkage studies have yielded putative TSC loci on chromosomes 9, 11, 12 and 16. Our current analysis, performed on 14 Dutch and British families, reveals only evidence for loci on chromosome 9q34 (TSC1) and chromosome 16p13 (TSC2). We have found no indication for a third locus for TSC, linked or unlinked to either of these chromosomal regions. The majority of our families shows linkage to chromosome 9. We have refined the candidate region for TSC1 to a region of approximately 5 cM between ABL and ABO.

PubMed Disclaimer

References

    1. Nat Genet. 1992 Sep;2(1):37-41 - PubMed
    1. Genomics. 1992 May;13(1):144-51 - PubMed
    1. Cytogenet Cell Genet. 1993;64(2):93-121 - PubMed
    1. Cell. 1993 Dec 31;75(7):1305-15 - PubMed
    1. Ann N Y Acad Sci. 1991;615:306-15 - PubMed

Publication types

LinkOut - more resources