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Review
. 1994 Jun;15(3):232-6.
doi: 10.1007/BF00123476.

The regulatory switch of the muscle thin filament: Ca2+ or myosin heads?

S S Lehrer  1
Affiliations
Review

The regulatory switch of the muscle thin filament: Ca2+ or myosin heads?

S S Lehrer. J Muscle Res Cell Motil. 1994 Jun.

Abstract

Ca2+ and myosin heads are both involved in regulation, with Ca2+ as the allosteric trigger and the myosin head-induced Tm off-on transition as the switch. The allosteric/cooperative model is a good phenomenological description of part of the process and aspects of the original steric blocking model are involved in the molecular mechanisms.

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References

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