Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Oct;57(10):1260-2.
doi: 10.1136/jnnp.57.10.1260.

DNA analysis in Finnish patients with hereditary neuropathy with liability to pressure palsies (HNPP)

K Silander  1 , P Halonen, R Sara, H Kalimo, B Falck, M L Savontaus
Affiliations

DNA analysis in Finnish patients with hereditary neuropathy with liability to pressure palsies (HNPP)

K Silander et al. J Neurol Neurosurg Psychiatry. 1994 Oct.

Abstract

Hereditary neuropathy with liability to pressure palsies (HNPP) is a dominantly inherited disorder that presents as recurrent mononeuropathies precipitated by apparently trivial traumas. The presence of a deletion in 17p11.2 was analysed in 13 Finnish families with HNPP. The deletion was found in all patients who were neurologically and neurophysiologically confirmed to have HNPP. In the problematic cases the detection of the gene defect is the method of choice in the diagnosis of HNPP. Analysis of DNA can also be used to detect clinically unaffected family members.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Neurology. 1965 Nov;15(11):1008-17 - PubMed
    1. Brain. 1972;95(4):777-94 - PubMed
    1. Brain. 1972;95(2):235-48 - PubMed
    1. Muscle Nerve. 1987 Sep;10(7):621-5 - PubMed
    1. Clin Chem. 1993 Sep;39(9):1845-9 - PubMed