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. 1994 Oct;80(5):705-12.

Reinterpretation of the genetics of susceptibility of Aedes aegypti to Plasmodium gallinaceum

V Thathy  1 , D W Severson, B M Christensen
Affiliations
  • PMID: 7931905

Reinterpretation of the genetics of susceptibility of Aedes aegypti to Plasmodium gallinaceum

V Thathy et al. J Parasitol. 1994 Oct.

Abstract

Several studies have demonstrated a genetic basis for variation in susceptibility of Aedes aegypti to Plasmodium gallinaceum. Although 25 yr ago it was reported that P. gallinaceum susceptibility in Ae. aegypti is determined primarily by a single autosomal dominant gene, evidence for additional genetic factors has emerged. Two sublines, 1 refractory and 1 of intermediate susceptibility to P. gallinaceum, have been selected from the Moyo-In-Dry strain (MOYO) of Ae. aegypti. Prior to selection, the MOYO population was 20.3% refractory. Genetic crosses of the highly susceptible Rockefeller strain (ROCK) and the 2 selected sublines of the MOYO strain provide evidence for a complex mode of inheritance of Plasmodium susceptibility in Ae. aegypti.

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