8-Hydroxypenillic acid: NMR characteristics and facile formation from 6-aminopenicillanic acid
- PMID: 7932059
- DOI: 10.1111/j.2042-7158.1994.tb03848.x
8-Hydroxypenillic acid: NMR characteristics and facile formation from 6-aminopenicillanic acid
Abstract
High field NMR (1H and 13C) spectral characteristics in D2O of 8-hydroxypenillic acid and 6-aminopenicillanic acid (6-APA)-sodium bicarbonate mixtures are reported. The ready conversion of 6-APA to 8-hydroxypenillic acid is demonstrated.
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