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Comparative Study
. 1994;41(3):187-9.

Effect of fibrosarcoma induction on copper and ceruloplasmin concentration in different organs of the host

P K Chakravarty  1 , A Ghosh, J R Chowdhury
Affiliations
  • PMID: 7935989
Comparative Study

Effect of fibrosarcoma induction on copper and ceruloplasmin concentration in different organs of the host

P K Chakravarty et al. Neoplasma. 1994.

Abstract

The copper content and ceruloplasmin activity were determined in mice bearing benzo(a)pyrene induced fibrosarcoma. The copper level and ceruloplasmin activity in different organs of fibrosarcomatous mice varied when compared to their controls. Significant changes in copper and ceruloplasmin concentration were observed in the liver and tumor tissue of host mice bearing fibrosarcoma compared to controls. Disturbed copper metabolism at the hepatic level may account for the hypercupremia observed during malignancy.

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