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. 1994 Oct 25;91(22):10502-6.
doi: 10.1073/pnas.91.22.10502.

Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation

I Ingelbrecht  1 , H Van Houdt, M Van Montagu, A Depicker
Affiliations

Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation

I Ingelbrecht et al. Proc Natl Acad Sci U S A. .

Abstract

Endogenous plant genes or transgenes can be silenced on introduction of homologous gene sequences. Here we document a reporter gene-silencing event in Nicotiana tabacum that has a distinctive combination of features--i.e., (i) silencing occurs by a posttranscriptional process, (ii) silencing correlates with DNA methylation, and (iii) this de novo methylation is not restricted to cytosines located in the symmetrical motifs CG and CXG.

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References

    1. Plant Mol Biol. 1991 May;16(5):821-30 - PubMed
    1. Annu Rev Genet. 1990;24:579-613 - PubMed
    1. Nature. 1982 Feb 18;295(5850):620-2 - PubMed
    1. Plant Cell. 1991 Dec;3(12):1327-36 - PubMed
    1. EMBO J. 1992 Jan;11(1):327-33 - PubMed

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