[The functional activity of the regulator region of virus SV40 integrated into recombinant plasmids]
- PMID: 7941017
[The functional activity of the regulator region of virus SV40 integrated into recombinant plasmids]
Abstract
We propose the system for transfection of eucaryotic SV40-based vectors. The method comprises simultaneous transfection of permissive monkey cells with plasmid DNA and the virus SV40. It is likely that the induction of replication of recombinant plasmids by the SV40 T-antigen is an indicator of functional activity of the SV40 regulatory region integrated into recombinant plasmids.