Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1994 Oct;220(4):436-41; discussion 441-4.
doi: 10.1097/00000658-199410000-00003.

A prospective randomized trial of total parenteral nutrition after major pancreatic resection for malignancy

M F Brennan  1 , P W Pisters, M Posner, O Quesada, M Shike
Affiliations
Clinical Trial

A prospective randomized trial of total parenteral nutrition after major pancreatic resection for malignancy

M F Brennan et al. Ann Surg. 1994 Oct.

Abstract

Objectives: The authors examined the impact of adjuvant total parenteral nutrition after major pancreatic resection for malignancy.

Summary background data: Previous studies have suggested a benefit to perioperative nutritional support for patients undergoing major gastrointestinal surgery.

Methods: A prospective, randomized study was conducted using patients who had undergone a major pancreatic resection with randomization on postoperative day one to either receive or not receive adjuvant total parenteral nutrition.

Results: No benefit could be demonstrated by the use of adjuvant parenteral nutrition in this setting. Complications were significantly greater in the group receiving total parenteral nutrition. These complications tended to be those associated with infection.

Conclusions: Routine applications of postoperative parenteral nutrition to patients undergoing major pancreatic resection for malignancy cannot be recommended. Further studies are required to determine the reason that infectious complications in these patients are increased.

PubMed Disclaimer

References

    1. Br J Surg. 1977 Feb;64(2):125-8 - PubMed
    1. J Surg Res. 1977 Jul;23(1):31-4 - PubMed
    1. Br J Surg. 1981 Feb;68(2):69-72 - PubMed
    1. J Surg Oncol. 1981;16(4):391-402 - PubMed
    1. N Engl J Med. 1981 Aug 13;305(7):375-82 - PubMed

Publication types