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Review
. 1994 Sep;15(9):393-9.
doi: 10.1016/0167-5699(94)90267-4.

The B-cell antigen receptor complex: structure and signal transduction

C M Pleiman  1 , D D'Ambrosio, J C Cambier
Affiliations
Review

The B-cell antigen receptor complex: structure and signal transduction

C M Pleiman et al. Immunol Today. 1994 Sep.

Abstract

The specificity of the immune response is determined by the interaction between the B-cell receptor (BCR) and its cognate structure, antigen. Recent studies have provided considerable insight into the compartmentalization of function within this extremely versatile hetero-oligomeric receptor complex. In this article, Christopher Pleiman, Daniele D'Ambrosio and John Cambier consolidate new findings regarding BCR structure and signal transduction.

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