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Review
. 1994 Aug 1;4(8):755-7.
doi: 10.1016/s0960-9822(00)00170-6.

Axis determination. Proteolytic generation of a morphogen

S Roth  1
Affiliations
Review

Axis determination. Proteolytic generation of a morphogen

S Roth. Curr Biol. .

Abstract

Ventral activation of a transmembrane receptor, Toll, is a crucial step in dorsoventral axis establishment in Drosophila embryos. The ventral ligand for Toll seems to be a proteolytic fragment of the Spätzle protein.

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