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. 1978 Jul;35(1):183-8.

Independent mobility of cholera toxin binding sites and Thy-1 alloantigen on mouse thymocytes

D De Cicco, M F Greaves

Independent mobility of cholera toxin binding sites and Thy-1 alloantigen on mouse thymocytes

D De Cicco et al. Immunology. 1978 Jul.

Abstract

The hypothesis that Thy-1.2 carries a carbohydrate antigenic determinant with the same specificity as the monosialoganglioside GM1 was tested by attempting to co-cap Thy-1.2 and GM1 in CBA thymocytes using anti-Thy-1.2 alloantiserum and cholera toxin. Co-capping of these determinants was not observed suggesting that they are on separate molecules. We do not therefore confirm the previous reported association between Thy-1 and GM1 (Thiele, Arndt & Stark, 1977).

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References

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