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Case Reports
. 1994 Aug;14(4):303-4.
doi: 10.1046/j.1468-2982.1994.1404303.x.

Octreotide dependency and headache: a case report

A May  1 , S Lederbogen, H C Diener
Affiliations
Case Reports

Octreotide dependency and headache: a case report

A May et al. Cephalalgia. 1994 Aug.

Abstract

We report on headache induced by a somatostatin octapeptide analog (octreotide) used for the treatment of acromegaly. This "rebound" headache has severe tension-type characteristics and occurs every 6-8 h. It resolves dramatically within minutes with octreotide administration. This is the first report of headache developing under treatment with octreotide.

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