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Review
. 1994 Nov;106(5):1624-6.
doi: 10.1378/chest.106.5.1624.

Granulomatous pneumonitis following intravesical BCG. What therapy is needed?

G P LeMense  1 , C Strange
Affiliations
Review

Granulomatous pneumonitis following intravesical BCG. What therapy is needed?

G P LeMense et al. Chest. 1994 Nov.

Abstract

A 68-year-old man developed fever, cough, and dyspnea after intravesical bacillus Calmette-Guerin (BCG). Chest radiograph revealed diffuse reticulonodular infiltrates with caseating granulomas on transbronchial biopsy specimen. Cultures were negative and the patient's condition improved with corticosteroids. The mechanism for BCG-induced granulomatous inflammation is poorly understood. Optimal therapy includes corticosteroids.

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