Replicating and host-restricted non-replicating vaccinia virus vectors for vaccine development
- PMID: 7958483
Replicating and host-restricted non-replicating vaccinia virus vectors for vaccine development
Abstract
Vaccinia virus, effectively used for immunization against smallpox, now serves as a recombinant vector for the development of vaccines against other infectious agents and cancer. Recent advances have led to increased gene expression, enhanced immunogenicity, and greater safety. Both replicating and host-restricted non-replicating vectors are available.
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