Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Nov;127(4):903-14.
doi: 10.1083/jcb.127.4.903.

HIV-particles in spermatozoa of patients with AIDS and their transfer into the oocyte

B Baccetti  1 , A Benedetto, A G Burrini, G Collodel, E C Ceccarini, N Crisà, A Di Caro, M Estenoz, A R Garbuglia, A Massacesi, et al.
Affiliations

HIV-particles in spermatozoa of patients with AIDS and their transfer into the oocyte

B Baccetti et al. J Cell Biol. 1994 Nov.

Abstract

By immunocytochemistry and in situ hybridization at the electron microscopy level, and by the PCR technique, we have shown that HIV-1 binds and enters normal sperm; that viral particles, their antigens, and nucleic acid are present in sperm from HIV-1 infected men; and that such sperm can transfer HIV-1 like particles to normal human oocytes. We also present evidence that a galactosylceramide-like compound is present on the sperm membrane and could function as an alternative receptor for HIV.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. FEBS Lett. 1990 Feb 26;261(2):339-42 - PubMed
    1. J Neurosci Res. 1989 Dec;24(4):548-57 - PubMed
    1. Fertil Steril. 1991 Mar;55(3):588-94 - PubMed
    1. J Submicrosc Cytol Pathol. 1991 Apr;23(2):339-45 - PubMed
    1. Science. 1991 Jul 19;253(5017):320-3 - PubMed

Publication types

MeSH terms