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Clinical Trial
. 1976 Dec;39(12):1219-21.
doi: 10.1136/jnnp.39.12.1219.

Nomifensine in parkinsonism

P F Teychenne, D M Park, L J Findley, F C Rose, D B Calne
Clinical Trial

Nomifensine in parkinsonism

P F Teychenne et al. J Neurol Neurosurg Psychiatry. 1976 Dec.

Abstract

Nomifensine, a tetrahydroisoquinolone antidepressant which facilitates dopaminergic and noradrenergic transmission, was studied in 28 Parkinsonism patients most of whom were also receiving conventional medications. Double-blind evaluations revealed a moderate therapeutic action at a mean dose level of 150 mg daily. Adverse reactions were encountered, similar to those identical by levodopa.

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References

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