doi: 10.1159/000276670.
Effect of 4 kHz tone exposure on the guinea pig inner ear: relation in the change of cochlear microphonics, action potential, electrochemical potential and K+ ion concentration induced by noise exposure
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- PMID: 7970610
- DOI: 10.1159/000276670
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Effect of 4 kHz tone exposure on the guinea pig inner ear: relation in the change of cochlear microphonics, action potential, electrochemical potential and K+ ion concentration induced by noise exposure
ORL J Otorhinolaryngol Relat Spec.
1994 Sep-Oct.
Abstract
Using 110 male albino guinea pigs, and applying electrophysiological methods, we investigated the effects of 4 kHz tone at moderate sound pressure level on the inner ear at different exposure times (6, 12, 24 and 48 h). Longer than 12 h exposure to 4 kHz tone had a considerable effect on the hearing, inducing a decrease in the maximum output voltage of cochlear microphonics and an increase in the K+ concentration in the endolymph.
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