doi: 10.1016/0092-8674(76)90134-3.
Recombination between bacterial plasmids leading to the formation of plasmid multimers
- PMID: 797459
- DOI: 10.1016/0092-8674(76)90134-3
Item in Clipboard
Recombination between bacterial plasmids leading to the formation of plasmid multimers
Cell.
1976 Dec.
Abstract
We report here the formation of plasmid multimers in E. coli. Multimers are covalently closed, circular molecules composed of tandem repeats of the monomer plasmid. Multimer formation occurs at high frequency in rec+, recB-C-, and recF- hosts. Multimer formation is not detected in recA- hosts and occurs at reduced frequency in recB-C-F- hosts. We conclude that multimer formation is mediated by a single reciprocal recombination event occurring at homologous regions on the two plasmids.
Similar articles
-
Plasmid-mediated lethality and plasmid multimer formation in an Escherichia coli recBC sbcBC mutant. Involvement of RecF recombination pathway genes.J Mol Biol. 1989 Oct 20;209(4):623-34. doi: 10.1016/0022-2836(89)90000-4. J Mol Biol. 1989. PMID: 2685325
-
Synthesis of linear plasmid multimers in Escherichia coli K-12.J Bacteriol. 1986 Jul;167(1):327-35. doi: 10.1128/jb.167.1.327-335.1986. J Bacteriol. 1986. PMID: 3522548 Free PMC article.
-
Lambda Red-mediated synthesis of plasmid linear multimers in Escherichia coli K12.Mol Gen Genet. 1990 Sep;223(3):496-507. doi: 10.1007/BF00264459. Mol Gen Genet. 1990. PMID: 2148608
-
Structural evolution of bacterial plasmids: role of translocating genetic elements and DNA sequence insertions.Fed Proc. 1976 Jul;35(9):2031-6. Fed Proc. 1976. PMID: 776704 Review.
-
Escherichia coli K-12 F-prime factors, old and new.Bacteriol Rev. 1972 Dec;36(4):587-607. doi: 10.1128/br.36.4.587-607.1972. Bacteriol Rev. 1972. PMID: 4568765 Free PMC article. Review. No abstract available.
Cited by
-
Recombinant plasmid that carries part of the nitrogen fixation (nif) gene cluster of Klebsiella pneumoniae.Proc Natl Acad Sci U S A. 1977 Jul;74(7):2963-7. doi: 10.1073/pnas.74.7.2963. Proc Natl Acad Sci U S A. 1977. PMID: 331321 Free PMC article.
-
Genome fusion mediated by the site specific DNA inversion system of bacteriophage P1.Mol Gen Genet. 1983;189(3):413-21. doi: 10.1007/BF00325903. Mol Gen Genet. 1983. PMID: 6602932
-
Homologous Recombination-Experimental Systems, Analysis, and Significance.EcoSal Plus. 2011 Dec;4(2):10.1128/ecosalplus.7.2.6. doi: 10.1128/ecosalplus.7.2.6. EcoSal Plus. 2011. PMID: 26442506 Free PMC article.
-
Plasmid stability analysis based on a new theoretical model employing stochastic simulations.PLoS One. 2017 Aug 28;12(8):e0183512. doi: 10.1371/journal.pone.0183512. eCollection 2017. PLoS One. 2017. PMID: 28846713 Free PMC article.
-
Sequence-specific recombination of plasmid ColE1.Proc Natl Acad Sci U S A. 1980 Nov;77(11):6724-8. doi: 10.1073/pnas.77.11.6724. Proc Natl Acad Sci U S A. 1980. PMID: 7005900 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
