Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1976;22(12):81-91.

[Role of prolactin in carcinogenesis and growth of mammary and breast neoplasms in animals and in man]

[Article in Russian]
N V El'tsina
  • PMID: 798416
Review

[Role of prolactin in carcinogenesis and growth of mammary and breast neoplasms in animals and in man]

[Article in Russian]
N V El'tsina. Vopr Onkol. 1976.

Abstract

PIP: Prolactin has an effect on the cells of the genetic organs. Experiments were conducted on the molecular mechanisms of the action of prolactin on normal, non-differentiated epithelial cells. One of the 1st effects of the action of prolactin is a stimulation of RNK synthesis. The action of prolactin also increases the activity of proteins I and II. The role of prolactin in the appearance and growth of malignant tumors of the mammary glands was studied in rats and mice with provoked chemical cancer. A treatment of metastasis in the cancer of the mammary gland in patients with a reduction of the level of prolactin is disucssed. Prolactin plays a role of promoter in the development of carcinomas in the mammary glands of animals with chemical and viral carcinoma; it speeds up the malignant process. Further studies are still necessary for the understanding of its significance in the carcinogenesis of human mammary glands.

PubMed Disclaimer

Similar articles

See all similar articles

MeSH terms