Case Reports
doi: 10.1016/0165-4608(94)90051-5.
Trisomy 11 and other nonrandom trisomies in congenital fibrosarcoma
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- PMID: 7987812
- DOI: 10.1016/0165-4608(94)90051-5
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Case Reports
Trisomy 11 and other nonrandom trisomies in congenital fibrosarcoma
Cancer Genet Cytogenet.
1994 Nov.
Abstract
Chromosome studies in a 7-week-old female infant with an intraabdominal malignant fibrosarcoma showed a hyperdiploid karyotype of 50,XX, +der(6)del(6)(p23)add(6)(q11), +8, +10, +11,add(12)(p13). Trisomy 11 appears to be a nonrandom primary cytogenetic abnormality in the congenital or infantile form of this mesenchymal tumor and is also a nonrandom gain in congenital mesoblastic nephroma. A possible developmental link between these two mesenchymal tumors, mediated by a gene or genes on chromosome 11 is postulated.
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