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Comparative Study
. 1978 Sep 9;2(8089):552-3.
doi: 10.1016/s0140-6736(78)92885-4.

Protective effect of dietary fibre against chemically induced bowel tumours in rats

D Fleiszer, D Murray, J MacFarlane, R A Brown
Comparative Study

Protective effect of dietary fibre against chemically induced bowel tumours in rats

D Fleiszer et al. Lancet. .

Abstract

101 rats were fed one of four diets containing graded amounts of dietary fibre. Subcutaeous dimethylhydrazine (D.M.H.) was given to half the rats in each of the diet groups. Stool mass was found to be directly related to the amount of dietary fibre consumed, and the incidence of D.M.H.-induced colon carcinoma was reduced as dietary fibre increased.

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