Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Sep;165(3):399-403.
doi: 10.1192/bjp.165.3.399.

Clinical features and diagnostic criteria of depression in Down's syndrome

S A Cooper  1 , R A Collacott
Affiliations

Clinical features and diagnostic criteria of depression in Down's syndrome

S A Cooper et al. Br J Psychiatry. 1994 Sep.

Abstract

Background: Depression occurs commonly in people with Down's syndrome, although there is little published about this association. This study explores the limitations of Diagnostic Criteria for Research, based on ICD-10 (DCR) and DSM-III-R depressive criteria.

Method: Case not examination identified 42 adults with Down's syndrome who have sustained 56 depressive episodes. The clinical features are reported.

Results: All episodes were diagnosed as depression. DSM-III-R criteria for major depressive episode were met by 50% of the episodes. DCR for depressive episode of at least mild severity were fulfilled by 68%.

Conclusions: These criteria were unduly restrictive for this group. Commonly occurring symptoms are not included in the criteria, while certain criteria items never occurred. Criteria should be modified to facilitate future research.

PubMed Disclaimer

LinkOut - more resources