Human centromere mapping using teratoma data
- PMID: 799523
- DOI: 10.1159/000130641
Human centromere mapping using teratoma data
Abstract
Under the assumption that benign ovarian teratomas arise parthenogenetically from a germ cell by suppression of the second meiotic division, the proportion gamma of heteratomas collected from heterozygous hosts is a measure for the distance between the corresponding gene and its centromere. For proportions gamma less than or equal to 0.3, the mapping function x = gamma/2 applies, where x is the map distance in Morgans.
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