[Angiotensin-converting enzyme inhibitor renography. Physiopathological, diagnostic and therapeutic aspects in renal artery stenosis]

Abstract

Angiotensin converting enzyme inhibitor renography (ACE-I-renography) can be used partly to screen for renovascular hypertension and partly to evaluate the possibility for successful revascularization. In patients with an important renal artery stenosis with a high intrarenal activity of the renin-angiotensin-system ACE-inhibition results in a change in renal haemodynamics which can be detected by renography. ACE-I-renography has a high positive and negative predictive value in diagnosing renal artery stenosis. Significant alterations in the renogram induced by ACE-inhibition in renal artery stenosis seem to have a good predictive value with regard to the effect of correction of the stenosis. ACE-I-renography is recommended in patients with arterial hypertension and a moderate or high probability for renovascular hypertension based on clinical criteria.