doi: 10.1007/BF01968610.
The mechanism of histamine release induced by the ionophore X537A from isolated rat mast cells. II. The relationship between increase of cell volume and histamine release
- PMID: 80105
- DOI: 10.1007/BF01968610
Item in Clipboard
The mechanism of histamine release induced by the ionophore X537A from isolated rat mast cells. II. The relationship between increase of cell volume and histamine release
Agents Actions.
1978 Jun.
Abstract
The ionophore X537A induced swelling of isolated rat mast cells parallel to histamine release. Both actions were depressed by extracellular calcium and BSA, temperatures below 37 degrees C, NEM, PMSF, and TTX, and were enhanced by high potassium and pretreatment of the cells with ATP. DSCG, theophylline, and DFP enhanced the histamine release noted after 10 min of incubation without influencing the swelling action of X537A. The swelling action could not be separated from histamine release and it is suggested that it might be inherent in the mechanism of secretion induced by X537A. The present results further distinguish histamine release induced by the two ionophores X537A and A23187.
Similar articles
-
The mechanism of histamine release induced by the ionophore X537A from isolated rat mast cells. I. Significance of monovalent cations, calcium, metabolic energy and temperature.Acta Physiol Scand. 1978 Mar;102(3):265-73. doi: 10.1111/j.1748-1716.1978.tb06073.x. Acta Physiol Scand. 1978. PMID: 77122
-
Swelling as a possible mechanism of action of X537A to release histamine from rat mast cells [proceedings].Agents Actions. 1978 Jun;8(4):387. doi: 10.1007/BF01968629. Agents Actions. 1978. PMID: 80110 No abstract available.
-
Mechanism of histamine release induced by the ionophore X537A from isolated rat mast cells.Int Arch Allergy Appl Immunol. 1978;56(2):179-87. doi: 10.1159/000232021. Int Arch Allergy Appl Immunol. 1978. PMID: 74363
-
Monovalent cation-dependent histamine release from rat peritoneal mast cells by ionophore X537A [proceedings].Agents Actions. 1978 Jun;8(4):394-5. doi: 10.1007/BF01968639. Agents Actions. 1978. PMID: 80114 No abstract available.
-
Modulation of the spontaneous histamine release by adrenergic and cholinergic drugs.Agents Actions. 1978 Jun;8(4):347-58. doi: 10.1007/BF01968614. Agents Actions. 1978. PMID: 80107 Review.
Cited by
-
The influence of hypertonicity on histamine release from isolated rat mast cells.Agents Actions. 1980 Apr;10(1 Pt 2):140-4. doi: 10.1007/BF02024197. Agents Actions. 1980. PMID: 6155767
-
Atropine and hexamethonium-sensitive, Ca/K-modulated, reversible swelling of mast cells in rat mesentery, due to feeding or exposure to carbachol.Agents Actions. 1988 Aug;25(1-2):4-10. doi: 10.1007/BF01969086. Agents Actions. 1988. PMID: 2903618
-
Valinomycin, a degranulating agent in rat mast cells which inhibits calcium-uptake.Agents Actions. 1987 Dec;22(3-4):189-96. doi: 10.1007/BF02009045. Agents Actions. 1987. PMID: 2451399