Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Apr;29(2):125-8.
doi: 10.1007/BF02358672.

Expression of the cholecystokinin precursor gene in rat tissues

A Funakoshi  1 , A Tanaka, T Kawanami, K Tateishi, K Miyasaka, A Kono
Affiliations

Expression of the cholecystokinin precursor gene in rat tissues

A Funakoshi et al. J Gastroenterol. 1994 Apr.

Abstract

Cholecystokinin, a brain gut peptide that stimulates gall bladder contraction and pancreatic exocrine secretion, also acts as a neurotransmitter. In this study, we demonstrated that small amounts of cholecystokinin precursor mRNA were expressed in the heart, lung, and kidney, as well as in the brain and the small intestine. The nucleotide sequences of the coding regions of the cholecystokinin precursor mRNA in these tissues were identical to those of the small intestine, indicating that cholecystokinin precursor proteins produced in these tissues are identical to those in small intestine. This is the first report demonstrating that the cholecystokinin precursor gene is expressed in the heart, lung, and kidney, as well as in the gastrointestinal tract and brain.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Nature. 1988 Jun 30;333(6176):858-60 - PubMed
    1. Proc Soc Exp Biol Med. 1991 Jun;197(2):175-80 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 - PubMed
    1. Nature. 1976 Dec 9;264(5586):568-70 - PubMed
    1. Proc Natl Acad Sci U S A. 1984 Feb;81(3):726-30 - PubMed

Publication types