Echocardiographic analysis of cardiac function during high PEEP ventilation
- PMID: 8014282
- DOI: 10.1007/BF01704696
Echocardiographic analysis of cardiac function during high PEEP ventilation
Abstract
Objective: Does positive end-expiratory pressure ventilation (PEEP) deteriorate cardiac contractility?
Design: By means of echocardiography nine piglets were studies during ventilation with 0, 15 and 25 cmH2O (PEEP). Recordings were made before and after 500 ml of 6% dextran 70.
Measurement and results: Right and left ventricular end-diastolic diameters were plotted against the stroke volume determined by the thermodilution technique. By combining observations made before and after volume expansion during the different ventilation modes, a ventricular function curve was obtained. The slopes of the curves were similar during all three ventilation modes, both on the left and on the right side.
Conclusion: This study indicates undisturbed myocardial contractility during PEEP ventilation. We infer that the cardiac output deterioration in the intact animal is caused entirely by impairment of venous return.
Comment in
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PEEP and ventricular function.Intensive Care Med. 1994;20(3):169-70. doi: 10.1007/BF01704693. Intensive Care Med. 1994. PMID: 8014279 No abstract available.
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