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. 1994 Mar;22(1-4):341-5.
doi: 10.1016/0169-328x(94)90064-7.

Distinct regulation of sodium channel types I, II and III following nerve transection

Y Iwahashi  1 , T Furuyama, S Inagaki, Y Morita, H Takagi
Affiliations

Distinct regulation of sodium channel types I, II and III following nerve transection

Y Iwahashi et al. Brain Res Mol Brain Res. 1994 Mar.

Abstract

We investigated mRNA expression of type I, II and III voltage-sensitive sodium channels in motoneurons following facial nerve transection by means of in situ hybridization histochemistry. Type I mRNA expression decreased markedly after nerve transection, while that of type III increased. Type II expression underwent no detectable change following nerve transection. These results suggest that type III sodium channels may be involved in regeneration and plasticity.

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