Micronutrient supplementation trials and the reduction of cancer and cerebrovascular incidence and mortality

Abstract

Epidemiological evidence suggests that a diet rich in fruits and vegetables may reduce the risk of various forms of cancer, most likely contributable to their vitamin and mineral content. It is believed that the vitamins and minerals in these foods contribute to a reduced risk of cancer. The population of Linxian, China is known to have one of the highest rates of esophageal/gastric cardia cancer in the world. Recent intervention studies from this particular geographic area for the first time have indicated that vitamin and mineral supplementation, specifically beta-carotene, vitamin E, and selenium, may play a role in the reduction of cancer risk.