Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1994 May;70(5):429-30; discussion 430-1.
doi: 10.1136/adc.70.5.429.

Attainment of normal height in severe juvenile hypothyroidism

K Minamitani  1 , A Murata, H Ohnishi, K Wataki, T Yasuda, H Niimi
Affiliations
Case Reports

Attainment of normal height in severe juvenile hypothyroidism

K Minamitani et al. Arch Dis Child. 1994 May.

Abstract

Prolonged juvenile hypothyroidism results in a permanent loss in height that is related to the duration of thyroxine deficiency before adequate thyroxine replacement treatment. A 13 year old girl with severe juvenile hypothyroidism was studied prospectively. She had an undetectable serum thyroxine concentration, a height SD score of -6.6 SD, and a bone age of 5.8 years. The enlarged pituitary gland involuted with thyroxine treatment to produce an empty sella. In addition to thyroxine the girl was treated with a gonadotrophin releasing hormone agonist to avoid the progression of puberty for 18 months and with growth hormone to achieve normal adult height.

PubMed Disclaimer

References

    1. N Engl J Med. 1988 Mar 10;318(10):599-602 - PubMed
    1. Pediatrician. 1987;14(4):246-52 - PubMed
    1. Arch Dis Child. 1991 Jul;66(7):838-40 - PubMed
    1. Horm Res. 1990;33 Suppl 4:38-44 - PubMed
    1. J Clin Endocrinol Metab. 1989 Aug;69(2):221-6 - PubMed

Publication types

LinkOut - more resources