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Review
. 1993 Oct-Dec;18(4):349-53.
doi: 10.1007/BF03190184.

The metabolism of ethosuximide

J S Millership  1 , J Mifsud, P S Collier
Affiliations
Review

The metabolism of ethosuximide

J S Millership et al. Eur J Drug Metab Pharmacokinet. 1993 Oct-Dec.

Abstract

The metabolism of the antiepileptic drug ethosuximide (3-ethyl-3-methylpyrollidine-2,5-dione) (I) in animals and humans is reviewed. Chiral aspects of the metabolism of ethosuximide are discussed. Clarification of the precise nature of the hydroxymetabolites of ethosuximide is presented.

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References

    1. Ther Drug Monit. 1990 Sep;12(5):514-6 - PubMed
    1. Biomed Mass Spectrom. 1978 Nov;5(11):601-3 - PubMed
    1. Drug Metab Dispos. 1973 May-Jun;1(3):569-76 - PubMed
    1. Clin Pharmacol Ther. 1976 Aug;20(2):213-8 - PubMed
    1. J Pharm Sci. 1974 Mar;63(3):467-9 - PubMed