Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1994 Jul;21(8):1179-85.

[Randomized controlled trial of MMC + UFT and MMC + 5-FU therapy in advanced gastric cancer]

[Article in Japanese]
T Sasagawa  1 , N Ho, T Endo, T Sekine, K Sugiyama, T Tomidokoro, S Hatakeyama, M Togashi, K Onuki, J Katagiri, et al.
Affiliations
  • PMID: 8031159
Clinical Trial

[Randomized controlled trial of MMC + UFT and MMC + 5-FU therapy in advanced gastric cancer]

[Article in Japanese]
T Sasagawa et al. Gan To Kagaku Ryoho. 1994 Jul.

Abstract

To compare the effects of MMC + UFT (A) with MMC + 5-FU (B) therapy on the response rate, survival time and changes with time in quality of life (QOL) in unresectable or recurrent gastric cancer, we carried out a study by a multicenter, randomized controlled trial from June 1990 to August 1992. 39 patients were randomly divided into A group and B group, including 6 incompletely evaluated cases and 3 in eligible cases. Responses were recognized in 3 out of 13 evaluable cases (23.1%) treated with regimen A and in one out of 15 evaluable cases (6.7%) treated with regimen B. Mean survival time was 150 days (A) and 116 days (B), respectively. These results suggested that MMC + UFT therapy is one of the effective regimens for advanced gastric cancer and as useful as MMC + 5-FU therapy. Moreover, it showed that regimen A was superior to B on QOL.

PubMed Disclaimer

MeSH terms

Supplementary concepts

LinkOut - more resources