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. 1993 Jan-Jun;39(1-2):9-11.

Atrial natriuretic factor in the ischemic heart

N Ionescu  1 , D Onicescu, S Muşat, O C Trifan
Affiliations
  • PMID: 8032027

Atrial natriuretic factor in the ischemic heart

N Ionescu et al. Rom J Morphol Embryol. 1993 Jan-Jun.

Abstract

The synthesis and the release of the atrial natriuretic factor (ANF) were studied by electron microscopy in the atrial cells from an ischemic myocardium. The ANF-containing secretory vesicles of normal atrial cells were present in great number near the Golgi apparatus, and near the sarcolemma. After 30 min. of global ischemia the number of ANF-containing secretory vesicles decreased in the atrial cells, suggesting an ANF release during heart ischemia.

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