Review
doi: 10.1016/s0959-437x(05)80055-3.
Position-effect variegation and the new biology of heterochromatin
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- PMID: 8032206
- DOI: 10.1016/s0959-437x(05)80055-3
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Review
Position-effect variegation and the new biology of heterochromatin
Curr Opin Genet Dev.
1994 Apr.
Abstract
The phenomenon of position-effect variegation has long been used as evidence for the importance of chromosome position to gene expression in eukaryotes. Investigations published within the past few years demonstrate that position-effect variegation is caused by multiple mechanisms, and that direct tests of hypotheses are possible with numerous model systems.
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