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Review
. 1994:35 Suppl 5:S81-4.
doi: 10.1111/j.1528-1157.1994.tb05976.x.

Tiagabine

Affiliations
Review

Tiagabine

H Mengel. Epilepsia. 1994.

Abstract

Tiagabine (TGB), a specific gamma-aminobutyric acid (GABA)-uptake inhibitor, is a potential new antiepileptic drug with a novel mechanism of action. In animal models of epilepsy as well as in a placebo-controlled trial in patients with complex partial seizures, TGB showed significant anticonvulsant effects. TGB was well tolerated by most patients.

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