doi: 10.1126/science.804182.
Fetal hemoglobin restriction to a few erythrocytes (F cells) in normal human adults
- PMID: 804182
- DOI: 10.1126/science.804182
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Fetal hemoglobin restriction to a few erythrocytes (F cells) in normal human adults
Science.
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Abstract
During adult life, the quantity of fetal hemoglobin (HbF) present in F cells--that is, rare erythrocytes which are reactive with rabbit antiserum to human HbF during microscopic immunodiffusion--is sufficient to account for all of the small quantity (less than 0.7 percent) of HbF normally present in whole blood. Thus, erythrocytes are normally heterogeneous with respect to the presence of HbF.
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