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. 1975 May;132(5):536-8.
doi: 10.1176/ajp.132.5.536.

Cogwheel rigidity related to lithium maintenance

B Shopsin, S Gershon

Cogwheel rigidity related to lithium maintenance

B Shopsin et al. Am J Psychiatry. 1975 May.

Abstract

Neurological examinations of 27 outpatients receiving lithium carbonate maintenance therapy for recurrent affective illness revealed that most of the patients receiving lithium for more than 8 months had cogwheel rigidity. The data suggest a positive correlation between the duration of lithium maintenance and the severity of cogwheeling. Intravenous administration of benztropine, an antiparkinsonian drug, did not abolish or significantly ameliorate this symptom.

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