Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994;76(2):141-51.
doi: 10.1016/0300-9084(94)90006-x.

Comparison of solution structure of free and complexed lac operator by molecular modelling with NMR constraints

E Gincel  1 , G Lancelot, J C Maurizot, N T Thuong, F Vovelle
Affiliations

Comparison of solution structure of free and complexed lac operator by molecular modelling with NMR constraints

E Gincel et al. Biochimie. 1994.

Abstract

The structure difference between the free operator of the lac system d(GCTCACAAT).d(ATTGTGAGC) and the same operator complexed to the headpiece of the lac repressor has been investigated by 2-D-1H NMR spectroscopy in conjunction with molecular modelling in internal coordinates (JUMNA). The free and complexed operator adopt both a right-handed B helical conformation, but a more detailed analysis of the conformational parameters using the Curves program shows striking differences in the groove geometries, the rises, the twists and the total bending.

PubMed Disclaimer

Substances

LinkOut - more resources