Hepatitis B antigen and prevention of post-transfusion hepatitis B
- PMID: 804765
- DOI: 10.1111/j.1423-0410.1975.tb02768.x
Hepatitis B antigen and prevention of post-transfusion hepatitis B
Abstract
Screening for hepatitis B antigen (HB-sAg) in the serum of blood donors and exclusion of antigen-positive blood units have reduced the frequency of post-transfusion hepatitis but several cases of hepatitis B still occur in association with transfusions. One explanation for this is probably that HB-sAg is not an indicator of infectivity. Thus healthy carriers of the antigen seem to have low infectivity while carriers with chronic liver disease as well as donors incubating hepatitis B probably present a great risk.
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