A new, mouse-myeloma immunoglobulin A having specificity for beta-D-(1 yields 6)-linked D-galactopyranosyl residues

Abstract

The discovery of T601, a new mouse-myeloma immunoglobulin A having specificity for beta-D-(1 yields 6)-linked D-galactopyranosyl residues, brings the total number of known antigalactan immunoglobulins to seven. The interaction of T601 with a number of ligands has been investigated. For those ligands showing interaction with the immunoglobulin, the affinity constants have been quantitatively measured by tryptophanyl fluorescence. The values show that protein T601 behaves very similarly to protein X24.