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Case Reports
. 1994 Mar;19(2):146-8.
doi: 10.1111/j.1365-2230.1994.tb01144.x.

Clinical and histological features of 'mechanic's hands' in a patient with antibodies to Jo-1--a case report

D Mitra  1 , C L Lovell, T I Macleod, R S Tan, P J Maddison
Affiliations
Case Reports

Clinical and histological features of 'mechanic's hands' in a patient with antibodies to Jo-1--a case report

D Mitra et al. Clin Exp Dermatol. 1994 Mar.

Abstract

The clinical and histological features of 'mechanic's hands' are described in a patient with polymyositis characterized serologically by antibodies to histidyl tRNA synthetase (Jo-1). Although described in the past in association with polymyositis, these distinctive cutaneous lesions have only recently been associated with the 'anti-synthetase syndrome'. It is becoming apparent that recognition of subsets within the spectrum of polymyositis/dermatomyositis characterized by certain clinical and serological features not only have prognostic significance, but also may provide insights into mechanisms of disease.

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